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Squalane: Your Ultimate Hydration Hero for Extremely Dry Skin

For a while now, squalane has ascended to the forefront, solidifying its status as a skincare hero.
For those struggling with extremely dry skin, squalane offers a powerful solution.
But what exactly is squalane and why has it become such a popular skincare ingredient? In this article, we take a deeper dive into squalane, exploring its benefits, compatibility with other active ingredients, potential side effects, and how to choose the right product for your skincare needs.

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What is squalane ?

Squalane is a naturally occurring substance in the human body and in some plants. It is a saturated and stable hydrocarbon that is derived from squalene, which is produced in the sebaceous glands of the skin.
Squalane is often used in skincare and cosmetic products for its moisturizing properties. It is known for its ability to hydrate the skin without leaving a greasy residue, making it suitable for all skin types, including sensitive and acne-prone skin.Squalane is also used in some pharmaceuticals and industrial applications.
It can be derived from plant sources such as olives, sugarcane, or wheat germ, or from shark liver oil, although the use of shark-derived squalane has become less common due to ethical and environmental concerns.

The Difference Between Squalene and Squalane

Squalene and squalane are both skincare ingredients derived from natural sources, but they have some key differences:

  • Chemical Structure

Squalene Squalene is a natural organic compound originally sourced from shark liver oil, though it can also be derived from plant sources like olives, amaranth seed, rice bran, and wheat germ. Chemically, squalene is a polyunsaturated hydrocarbon with the formula C30H50.
Squalane Squalane is the hydrogenated form of squalene. This means it has been chemically modified to make it more stable and less prone to oxidation. This stability makes it a preferred choice in skincare products. Squalane has the same chemical formula as squalene but with additional hydrogen atoms.

  • Source

Squalene Traditionally sourced from shark liver oil, which has raised ethical and environmental concerns due to overfishing and its impact on shark populations. However, it can also be sourced from plant-based alternatives.
Squalane Generally derived from squalene through hydrogenation, which can be sourced from both animal and plant-based sources, but plant-based squalane is more common and preferred due to ethical and sustainability reasons.

  • Properties

Squalene Squalene is highly prone to oxidation, meaning it can degrade when exposed to air and light, leading to an unpleasant odor and potential skin irritation.
Squalane Squalane is more stable than squalene, making it less prone to oxidation. This stability allows it to have a longer shelf life and be more suitable for skincare formulations. Squalane also has excellent emollient properties, meaning it helps to soften and smooth the skin without leaving a greasy residue.


In summary, while squalene and squalane are closely related compounds with similar skincare benefits, squalane is the more stable and preferred form due to its resistance to oxidation and sustainability concerns associated with traditional squalene sources.

The benefits of squalane

Squalane is a natural moisturizer and emollient that offers numerous benefits for the skin. Here are some of its key advantages:

Excellent Moisturization Squalane is highly effective in hydrating the skin. It forms a protective barrier on the skin’s surface, preventing moisture loss and keeping the skin hydrated and supple.

Non-Comedogenic Squalane is non-comedogenic, meaning it does not clog pores. This makes it suitable for all skin types, including acne-prone and sensitive skin.

Softens and Smoothens Skin Squalane has a lightweight texture that allows it to penetrate deeply into the skin, softening and smoothing it. Regular use can help improve the skin’s texture and overall appearance.

Antioxidant Properties Squalane has antioxidant properties, which help protect the skin from free radical damage caused by environmental stressors such as UV radiation and pollution. This can help prevent premature aging and maintain youthful-looking skin.

Anti-inflammatory Squalane has anti-inflammatory properties, making it beneficial for soothing irritated or inflamed skin. It can help reduce redness, swelling, and discomfort associated with various skin conditions.

Enhances Skin Barrier Function Squalane reinforces the skin’s natural barrier function, which is essential for maintaining optimal skin health. A strong skin barrier helps protect against external aggressors and prevents moisture loss.

Can You Use Squalane With Other Active Ingredients?

Squalane is a versatile and stable ingredient that works well with various other active ingredients in skincare formulations. Some ingredients that synergize effectively with squalane include:

Hyaluronic Acid Hyaluronic acid is known for its hydrating properties. When combined with squalane, it can help boost skin hydration, leaving the skin plump and moisturized.

Antioxidants Ingredients like Vitamin C, Vitamin E, and Coenzyme Q10 are potent antioxidants that help protect the skin from free radical damage. When combined with squalane, they can enhance its protective effects against environmental stressors.

Retinol (Vitamin A) Retinol is a well-known anti-aging ingredient that promotes cell turnover and collagen production. Squalane can help mitigate potential irritation from retinol while also providing moisturization.

Peptides Peptides are amino acid compounds that can support collagen production and improve skin firmness. Combining peptides with squalane can enhance the overall anti-aging effects of skincare products.

Niacinamide (Vitamin B3) Niacinamide offers multiple benefits for the skin, including improving the skin barrier function, reducing inflammation, and minimizing the appearance of pores. Squalane can complement these effects by providing moisturization and enhancing skin barrier repair.

Ceramides Ceramides are lipid molecules that help maintain the skin barrier and prevent moisture loss. Squalane can work synergistically with ceramides to reinforce the skin’s natural barrier function, keeping it hydrated and protected.

Alpha Hydroxy Acids (AHAs) and Beta Hydroxy Acids (BHAs) AHAs like glycolic acid and BHAs like salicylic acid are exfoliating agents that help remove dead skin cells, unclog pores, and improve skin texture. Squalane can help mitigate potential dryness or irritation caused by these acids while providing moisturization.

Potential Side Effects of Niacinamide

Squalane oil is widely regarded as a safe skincare ingredient suitable for the majority of individuals. Nonetheless, akin to any other skincare product, there exists a possibility of skin irritation or allergic reactions associated with its usage.
It is recommended to conduct a patch test prior to incorporating squalane oil into your skincare routine. This involves applying a small amount to a discreet area of skin, such as the inner arm, to assess any potential adverse reactions. Should you experience symptoms such as itchiness, swelling, redness, or irritation, it is imperative to discontinue use immediately.

What criteria should you consider when choosing a product ?

When choosing a skincare product containing squalane, there are several important criteria to consider to ensure that the product is effective, safe, and suitable for your skin type. Here are some key factors to keep in mind:

Ingredient Quality and Purity Ensure that the squalane used in the product is high-quality and sourced from reputable suppliers. Look for products that contain pure squalane derived from plant sources like olives or sugarcane.

Concentration of Squalane Check the product label to see where squalane is placed in the ingredient list. Higher concentrations of squalane typically mean more potent and effective moisturization.

Additional Ingredients Consider other ingredients in the formulation. Squalane often works well with other hydrating and nourishing ingredients such as hyaluronic acid, glycerin, ceramides, and antioxidants like vitamin E or green tea extract. Ensure that these ingredients are also suitable for your skin type and address your specific skincare concerns.

Skin Type Compatibility Determine if the product is suitable for your skin type. Squalane is generally well-tolerated by most skin types, including sensitive and acne-prone skin, due to its lightweight and non-comedogenic nature. However, individuals with specific skin conditions or allergies should still check for potential irritants.

Texture and Formulation Consider the texture and formulation of the product. Squalane can be found in various skincare products such as serums, oils, moisturizers, and creams. Choose a texture that suits your preferences and fits well into your skincare routine.

Squalane emerges as a remarkable skincare ingredient with a multitude of benefits for all skin types.
Its ability to hydrate, protect, and restore the skin’s natural balance makes it a standout in the realm of skincare.
As we strive for healthier and more radiant skin, integrating squalane into our routines shouldn’t be a choice to ponder over but a decision to embrace wholeheartedly. With its gentle yet effective nature, squalane promises to revolutionize your skincare regimen, offering a path to smoother, more nourished, and youthful-looking skin.
Don’t hesitate to welcome this wonderful ingredient into your daily routine—it’s a game-changer you’ll be glad you discovered.

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